The answer is no. The reason for it is, that Oculus should and does, for the most part, take care of everything. There are however, a number of things I like to explicitly declare myself.
Commands I usually explicitly execute at the start of a VR game:
hmd qahead on (improve performance, docs here)
hmd timewarp on
hmd mirror mode 1 (undistorted stereo view, for best performance - turn mirror off “hmd mirror off”)
hmd pd 1.0 (Sets pixel density in the center (default is 1.0) - lower for better performance, higher for better quality)
r.HZBOcclusion 0
r.FinishCurrentFrame 0
r.RHICmdBypass 0 (enable multi-threaded renderer)