So after some testing this seems to work but it will either add to or reduce latency a bit depending on settings. Once plugin is installed and activated just add an event on begin play that sets DLSS mode to balanced or performance in level blueprint. It only manages between 0.5ms and 1.5ms improvement in one project but in others it made things worse…
I also set project to DX12 which seems to give a boost though again depends on project. I would also recommend turning off GPU scheduling in windows and any game overlays plus install latest drivers.
I don’t think it works as well as normal games because you’d expect much more of a boost really. It works great in the viewport and gives massive gains there but not much for VR right now.
Perhaps it hasn’t been optimized yet by nvidia? Hopefully others more knowledgable can make sense of it?