Hello there @OneNot!
Checking around the community, the DLSS failed pipeline error you are getting is usually related to a graphic conflict, either with the active DX, or the current video drivers in your system. Please test the following steps:
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First, the most usual solution, perform a clean install of your current drivers using any free uninstaller tool, then update to the latest version. If available, please use Developer drivers.
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Then, ensure your OS has the latest updates installed ,as well as your DLSS plugin version. Confirm the one you are using is compatible with your UE install.
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Once all updates are done, if the issue persists, the next step is to perform a cache clear in your project. Go to it’s main directory, and delete folders Saved, Intermediate, and DerivedDataCache. After that, restart your project, and allow the shaders to recompile.
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At this stage, you can also try switching between DX11 and DX12.
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Finally, if the problem is not resolved yet, it could be tied to the project itself. In order to know this, open a blank project, add the same DLSS plugin build, and test if the issue re-appears.
For further methods to test, please check the related scenario below: