Hello ,
If you’re looking to run your game with the Visual Studio debugger attached without running the editor, the best configuration would be Debug_Game. Are you using Visual Studio 2015?
As far as spaces go, they should only create problems if you have your project folder (the one above it is fine), project name, or any files in your project with spaces in them. This shouldn’t be the cause of your issue.
Usually when I see this error, it’s from trying to run a launch a packaged game from the editor without building for Development (not Development Editor), so it’s odd that you’re getting this error in this case. Let me know if you continue to get this with Debug_Game.