When pressing "Launch Session" within the Unreal Editor, an error message "Failed to initialize Dependency Modules" pops up and the game does not start within Fortnite.

General Issues and Bug Reporting
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Unfortunately I have the same problem which only started on the 8th of July this year and it is a map created with UEFN over the last 2 months, hoping it can be fixed as a lot of work has going into the map so far and it still is not finished yet.

https://forums.unrealengine.com/t/launching-a-session-i-get-failed-to-initialize-dependency-module-is-there-a-fix-for-this/1223448