I have been having this issue (whole pc locks up, have to restart) in the UE 5.1.1 editor as well. It happens pretty frequently (immediately after starting the editor from VS code this morning and twice yesterday in 8 hours of constant use).
I have a 1080TI on the latest driver. I just tried changing RHI to DirectX 11 since I saw that mentioned as a temporary solution in this thread.
Have you had the issue since upgrading to Unreal 5.3.1? I see you posted that 25 days ago so fingers crossed!