While I can’t see any technical reason this wouldn’t work, keep in mind that normal maps rely quite a lot on being high resolution and sometimes high bit depth to offer good quality shading. Loading 60 into memory all at once for a single object is not great. Most games with animated normals have a small number that they cheaply lerp between (such as the clothing in GTA).
You can also achieve rotation with some math, and panning is trivial. A mask could be made to apply each of these effects in different spots to create pretty advanced looking animations without needing multiple frames.
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