To recreate this, i am finding that opening up 2 different projects with the same engine version (4.22 for me) will lead to one of them crashing after a while. Windows 10 will block the application from accessing the graphics hardware which triggers the crash. It does seem to go in order of opening. Like so:
Open Project A
Open Project B
Project A crashes after several hours
Open Project A again
Project B Crashes after several hours.
I have improved the uptime of both projects to a day ( so now I only have a daily crash) by turning of SLI mode for UE4Editor.ext in 4.22 folder. The SLI mode is set to maximise performance on Nvidia Control Panel.
I do not have any crashes in UE4 games, just the editor.