Yes, you can go into the master material, and change each texture to a virtual texture. Then Virtual options will show up under Sampler Type. Change Color to Virtual Color, Normal to Virtual Normal, etc.
But I wouldn’t do it unless you need the memory.
VT costs more GPU in exchange for saving memory.
It’s a bug that there’s no way to stop Quixel from importing VT if we have VT enabled.
As someone said VT isn’t a replacement, but an option that allows us to do other things, like use huge textures.