Performance will be different if you play in editor or in standalone/packaged. If you play in editor then the whole editor will still run and use up performance, therefore if you profile performance, better use standalone otherwise you will get (severely) wrong results due to the editor and all the windows you have open there using up performance.
There may also be a bit difference between standalone and packaged and between different package configurations, but 40fps to 80fps sounds a bit large for standalone vs packaged…