I had the same issue, when I would activate landscape mode it would bsod.
I figured out the issues,
#1. Make sure if running an nvidia gpu to install studio drivers
#2. Disable any cpu over locking
#3. Disable AMP profile
#4. Disable gpu overclocking
#5. Create a large page file in windows, I set mine to be 4000mb to 8000mb
#6. Make sure you have Visual Studio with the proper coding compilers installed.
Now reboot.
Unreal Engine should work as it should.