Particles collide with a destrucible mesh

Hi everyone ! :slight_smile: I would like to know If its posible to create a mesh particle system and make it collide with a destructible mesh ? All of this inside sequencer. I have a character who create a dark magic ball and I have animated to movement of the particle system by hand in sequencer but when I play nothing happen the ball go throught the wall. I tried with a simple sphere not a particle and it works. But I need to make it with particles ^^’
If you have an idea it will be a pleasur to read you :slight_smile: