Sorry about waking up an old post but I was looking for something similar for some hours now, and I found on another post something which could be useful in that case and without using MPC, dynamic material and blueprints, only a node in the Material editor.
So, i’m posting it here, just in case someone was in the same case as me and arrive on this post while asking google “offset UV UE4” or “moving dynamically UV in UE4” etc…
And here is my saver : The node “Panner”.
You have to put the pin out of the “TexCoords” in the “Panner” and then “TextureSample”. Easy and less cost than dynamic material apparently ! =)
It also exists another node named “Rotator” to rotate these UVs in real-time.
=) Hope it helps another nooby like me ! =)