For anybody reading this: in my case (building a VR simulation) the crash was caused by the combination of
- DirectX 12,
- using a DrawDebug statement in a BP and
- running on a GTX 1080.
This combo runs fine on another system with an 4070 onboard.
Switching the Default RHI to DirectX 11 resolved the crash but resulted in lots of flickering (not very useful so the DrawDebug will have to go).