Crazy crash happening in 5.3: "LogRHI: Error: Breadcrumbs 'RHIThread'"

EXCEPTION_ACCESS_VIOLATION reading address 0xffffffffffffffff

is usually a memory issue. Either you have a null pointer and it can’t access that part of memory or it’s a hardware problem

Try adding the debug symbols to your engine

We might get some better info what is causing it.
Can you try it out on another pc to check if it may be a memory problem?