Cinema 4D Workflow

Not sure what you’re talking about Antidamage.
I use my mouse all the time to arrange UVs.

The only things i really miss is the ability to work with a customizable grid (e.g. for Lightmap creation)
and that neat UV join feature where you just select an edge and have the adjacent UV piece snap to it automatically.
(i think i saw that in 3dsMax)