Can you use particles as projectiles?

As title - is there any problems with using particles as projectiles (causing damage to player etc)? I’m still nooby with game creation but experience and a love for particles coming from 3dsmax.

I’m aware that GPU collisions dont happen if the object is culled, but there is a workaround with the distance-ambient-occlusion-thing (cant remember what its called)

if someone could chime with the pros and cons that would be great - i’m thinking if I can do a simple ‘particle = x damage’ then an acid spray would just kinda work without doing much extra work. Am i correct in that assumption? Nothing ever seems to be as simple as I think it will

After some googleing (is this a word?) i stumbled over this thread, maybe it helps: