Hi @diadntjr! Let’s see if we can figure this one out.
The error you are receiving has multiple causes/sources, we will cover them one by one:
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For registry changes, the recommended value for TdrLevel and TdrDelay is 60, this will give your PC plenty of time to respond to a possible freeze.
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When updating your nVIDIA drivers, make sure you are picking the “Clean Installation” option, as well as going for the “Developer” drivers, as these have more stable settings for engine work.
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Windows update is self-explanatory, simply make sure you are up to date, as you already did.
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In Unreal Engine, reduce the values for engine scalabillty, to ensure your equipment is not being exerted.
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Make sure no RTSS or overlocking are enabled for your video card.
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Alternatively, another user with a similar scenario reported that undercloking the video card just a bit, ensured stability on his work. You can check said thread here.
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UE provides a few more advanced methods in this thread.
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Finally, it can all come down to a hardware issue, please make sure your GPU has proper maintenance and good airflow.