I had a similar problem, and I checked the following to get things going.
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I had recently plugged my Xbox One controller in, so possibly it didnt detect right away
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Can you move around in the editor view (not playing the game) with the controller? It should fly around like WASD
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When you start the game, have you clicked on the window to focus it so it takes input?
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Try running the game outside of the editor and see what happens.
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Open the blueprint while playing your game which listens for controller input and check to see if connections are firing.
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You may also have an event which consumes the input and isn’t sharing with other event calls
Hope that helps 