Just for the record: Same on all machines here with binary 4.16.1. This should not be marked fixed unless it actually is. Sadly, the workaround doesn’t yet do the trick for me either.
From my investigation, the issue is a little broader and not restricted to ICU. I have managed to trick a debug game into finding ICUs content dir by copying the Internationalization folder into the game’s content. Yeah, I know… Anyway, after that the initialization phase skipped with that:
Fatal error: [File:D:\Build++UE4+Release-4.16+Compile\Sync\Engine\Source\Runtime\Engine\Private\PhysicsEngine\PhysXLibs.cpp] [Line: 87]
Failed to load module ‘…/…/…/Engine/Binaries/ThirdParty/PhysX/Win64/VS2015/PxFoundationPROFILE_x64.dll’.
Which means the next dynamically loaded module also wasn’t found. I believe the reason is that FPaths::GameContentDir() and FPaths::EngineContentDir() don’t seem to work in debug builds, causing all those subsequent errors.