Understanding the format of material editor UVs

I’m not sure if you’re just giving me a definition of UVs, or if you’re actually trying to explain to me what I want to know and I don’t get it.

Let’s say I have this generic sprite sheet texture. I want to map the part that’s inside the red square to a flat mesh with 4 vertex points. I create a material and I assign it to this mesh. What do I need to pass in the UVs parameter of the TextureSample node in the material editor? Without using the FlipBook node.

uvs2.png