Sorry, didn´t explicitely mention this, but my Vram was sitting comfortably at 6GB when it crashed, on an rtx 3090, which has 24GB, so I really don´t think Vram is the issue.
It might spike for some unknown reason, something like cache being emptied before loadinga scene etc, but thats not something I would know, only devs could answer that.
I have never heard that normal Ram would cause this, but I have 64GB and I´m pretty sure it also wasn´t maxed out when it crashed.
I might wanna dig deeper into the new profiling tool though, maybe it helps figure this out…