In Cascadeur the animation look well, in Blender and in Autodesk too, just in unreal i have this problem, I try in FBX 2020 and in FBX 2013 but i get the same results in Unreal Engine 5.5.1
After giving it a lot of thought, it is 100% a problem of how unreal manages the position of the pelvis with respect to the root, any position of the root that is not under the pelvis completely breaks the position of the animation.
Update: It only happens if I animate with the Metahuman skeleton, I re-animated with the SK_Mannequin and retargeted them and everything works as it should.