Figured out this is not a bug and is intended behavior. An instance of B_MannequinsXR is used as the left and right hand in VRPawn. The left hand instance has to have the default property of “Mirror” set to True and the Right hand set to False manually in VRPawn.
If you change the “Mirror” value in the B_MannequinsXR blueprint, it will set both the left and right hand instances in VRPawn to either true or false which is what caused my issue.