HISM still have the underlying weight of LOD (the meshes and textures or mips to display them.) So even if nanite disabled the additional LOD work, ISMS (HISM is a collection of ISMs), you would still have the impact on memory. Using ISMs, if you are always enforcing nanite, is better than HISM. HISM used to have a culling advantage in UE4, but in UE5 ISM got that same culling, so if using nanite, ISM is king.
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