Since updating to 4.10.2, project fails to load

If it is a C++ project the error means your classes are failing to compile due to coding errors (some classes and function calls change when the engine gets updated). You should get into your code and check what should be change so you can compile it for 4.10. Also 4.10 requieres the latest version of Visual , so that might be causing the problem too.

Check this forum thread:

If you were already on 4.10 this might be a content error. Try creating a new project and add your code to it. if it compiles, start moving your content to it on small bulks to try and narrow down the possible problem.