There are two situations you’ll likely see this error:
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you are trying to launch the editor, but accidentally have DebugGame selected (instead of DebugGame Editor).
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You are trying launch DebugGame (without editor) but you’ve yet to package your project. Essentially when you run DebugGame it will go and look for files in your binary folders (I think) to run your game. If you’ve not gone to File > Package project, you are likely not to have the required files. The package process creates these files. Be sure that you go into Package settings and select the appropriate target (for example, if you’re trying to launch Debug Game, then you should change it from the default of Shipping to Debug Game)