Problem with setting spawn point!

Hey,
I’m struggling with a game which is like “Guitar-Hero” (tiles are raining down from the top of the screen and you have to tap a button early enough).
But I’m failing at setting the spawn, because the spawn point and the point where the player should press the button is different whenever you change your screen size.
Also all 5 off my buttons on the bottom are messing up because of this.
I’m really struggling with that, please help me.

-Creey

Yes, I’m using UMG.
It’s only for one player, my button are anchored to the bottom of my screen.
I have a fixed spawn and death point, but that’s the problem, because when my screen size changes the points are sometimes not on the screen or in the middle of the screen (because they are not dynamic).
I want that they spawn on the top of the screen and that they will be destroyed when they are at the location of my button.
Is this understandable?

Ok I hope some one else can help me with this problem or can tell me some tricks.
But thanks for the response 1999!