Need help to game-design ship movement/fight system with restrictions

Hello. I want to create a game system for ship movement / fights. But I have restriction - the player should be able to use only one hand, so all the actions should be connected to mouse or WASD area. Gameplay: player’s ship is exploring the sea, fighting with others ships, looking for treasures on islands. The player is a captain of the ship. The main reference is Assassin’s Creed Black Flag. The ship should have the ability to use cannonballs, buckshot, etc. The captain have abilities too: encourage for damage boost, fear for speed boost, etc. So, what is the better way of gameplay organization to make it look good and keep good control? I’m thinking about turn based combat, but it seems too inappropriate for that kind of gameplay.