Nanite breaks tangents

I was testing our baking system in Substance Designer and wanted to check if our normal maps are still synched with unreal.
By default, Nanite support is enabled and the result is wrong.

Disabling Nanite shows a correct result:

Am I doing something wrong? Is this a bug in Nanite ?

I think you need to check explicit tangents on the right under nanite. There’s an assumption with nanite that you’re going to use enough geo that you don’t need normal maps for anything but detail normals.