Is there a way to use the advantages of Nanite on the one hand and vertex painting on the other?
I have always used the same master material for many environment meshes and then painted in moss, cracks, wetness etc. with vertex color.
However, once I have turned a mesh into Nanite, this no longer works. What is the best solution for this?
I would be very happy about your answers 
You can try other approaches for texture variation, like world position, decals, surface direction, distance fields, per instance random, per instance custom data, etc.