My quixel and unreal marked place dont open.

That is… quite odd. I’ve been digging around similar threads to see what other fixes have come up, but there’s not too many other than reinstallation which you’ve already done. Is there any logs/errors happening when trying to launch the it?

One thread mentions removing it from this plugin instance location, but then going to your vault and adding it from there.

I’ll pull some info from a closely related post (not 100% the same issue):

Check your Timezone Settings:
 
Make sure that both set time automatically and set timezone automatically are checked in order for Bridge to run efficiently. If these settings are not in place, you will be faced with a blank screen when you launch Bridge. 

For Windows: Settings > Time and Language.

Local firewalls (e.g. Windows Firewall) or Antivirus programs:

Bridge requires admin rights (on Windows) and unrestricted internet access. Make sure local firewalls (e.g. Windows Firewall) or antivirus programs are not interfering with your connection or blocking Bridge and/or Unreal Engine 5.
 
Here is an article explaining how to allow/block applications in windows firewall How To Allow Or Block Apps In Windows Firewall in Windows 10.
Before running Bridge, right click on Bridge icon and select "Run as Administrator".

 

Bridge Clean Revamp 

Some users have reported that a clean reinstallation of Bridge has fixed this issue for them. Please follow the steps below to revamp Bridge:

1. Close Unreal Engine, if already running!

2. Go to C:\Users\<username>\AppData\Local\UnrealEngine\5.0 and delete the DerivedDataCache folder. 
 
3. Go to Epic Games Launcher>Unreal Engine>Library, click on the "installed plugins" option under Unreal 5.0.2, and remove the plugin.
 
4. Now go to <Epic Games>\UE_5.0\Engine\Plugins and delete the folder titled "Bridge" from there.
 
5. Go back to Epic Games launcher>Vault and you'll see the option to reinstall Bridge from there. Install it to the Engine. (Make sure UE5 is closed)
 
6. Run Unreal Engine and see if the issue is resolved. 

Another user had an issue where the window itself was just hidden and the only way to reset it was to try and launch it, check if the window exists by hovering the unreal icon in the taskbar, if it has another instance that’s blank looking you have to remove the plugin, launch the project so the window crashes, then close and reinstall the plugin. After this it should relaunch in a fresh window on the primary monitor.

Disclaimer: One or more of these links are unaffiliated with Epic Games. Epic Games is not liable for anything that may occur outside of this Unreal Engine domain. Please exercise your best judgment when following links outside of the forums.

Another thread with some possible fixes:

Reference thread from previous answer:
https://help.quixel.com/hc/en-us/community/posts/7414377400733-UE5-0-3-Quixel-Bridge-not-loading

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