Multiple different scenes in the same place

What would be the best way to set up multiple different potential scene set ups in the same location on a larger map?

Essentially my situation is this: I have a map (not streaming), and in one room, when you get there, one conversation out of a long list of them is available. Depending on the available conversation, the NPCs in the room will be in different places, playing different animation loops.

I could just have a blueprint move things around according to values in a list, but that seems silly. Being able to graphically place things would be ideal.
I could do multiple sequencer scenes, but I don’t really require a sequence, just the initial setup.
I could do something with streaming levels? But that seems a bit excessive for just one room of the map. Maybe it just seems wrong due to my unfamiliarity with them.

How would you set this room up?