Losing actor references in sequencer during play or simulation

I have a project under Unreal Engine 5.1. If I add a level sequence to my level and simply add an actor to the sequencer everything seems to be fine. If I play or simulate the level, the icon for my actor in sequencer turns red and I seem to lose the reference to the actor. If while playing or simulating, I Fix Actor References, it seems to fix them but when I stop the simulation, the original references are lost.

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The strange thing is that this is not happening in all projects. If I create a new project and simply add a cube and then I add a level sequencer, add the actor to the sequencer and play the level, the reference seems to work fine. But in my existing project, the exact same steps produce the result mentioned above.

Thanks!

Same problem here. Was your existing problem migrated from 5.0?