I usually stick with ASUS. MSI makes some decent parts but ASUS has been around for a while and their durability and reliability is good. Alienware went down hill when Dell bought them out, they may be better than when they were first bought by Dell but they still seem to share memory a little too much for my liking. My only complaint about ASUS is that it will get very hot, or at least my ROG does. It has never overheated but has only been under constant load for a few hours at a time. Remember laptops really are not well suited for long heavy loads, if you are looking to do a lot of gaming and long periods of it, I would recommend that you get a desktop. If you really need the mobility then I think the ASUS will do just fine.