If you have to ask this question with that comparison, then no, UE4 will not limit you in any way.
I’m not trying to be rude by any means, but Rockstar had a lot of people and a lot of money. Is UE4 capable under those circumstances? Yeah. If you have those circumstances then you wouldn’t be here asking us.
Ultimately, UE4’s performance and quality is incredible. I take that’s the answer you wanted.