Is there a way to make a material's "Two Sided" checkbox a parameter?

It is automatically a Parameter in your Constant Material Instances. You can’t change it at runtime.

Create a Material Instance out of your One-sided Material. Under Material Property Override you can override the Two-Sided Property.

You can then create a Dynamic Material Instance out of this Material Instance.
As I mentioned, you can’t set the Two-Sided at runtime! You have to change the Material (/-Instance) if you want to switch between Two and One sided

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