Is it possible to have multiple actors use the same (instanced) mesh?

To clarify: I want to have many individual actors in the scene but they shouldn’t use one draw call each. Every actor has an instance of a mesh and all of the instances are rendered using just a few draw calls.
Is this possible?

Yeah, with foliage tool ))

You can also try to use blueprint with one ISM component, and array of editable transforms that you will use for every instance.