Inputing images into game and have Substance Designer textures update live

I’m wondering if it’s possible to automate a way of modifying substance designer texture parameters and update the textures with python scripting on a running build of Unreal Engine.

I was wondering if its possible to take a picture that automatically gets pulled into Substance Designer and exported/modified back to an Unreal playable real time final build and have it appear in the game as an updated texture.