@dnwalkup Yeah, I did some testing on this yesterday with good results. It’s not quite “drop-in” but I got good results on a pbr painted test sculpt without too much extra work. Thread here: UVs and Nanite
One thing is to make sure of is that you check the checkbox for Nanite when you import the mesh, since otherwise it’ll just be treated like a standard pipeline mesh, which makes UE5 very unhappy if it has millions of tris.