How to save data when there are multiple SSDs

First of all, please understand that I am not familiar with English.

I’m using After effects and have multiple storages.
Below is the storage I have.

① OS and application (PCI-Express Gen3 1TB) 3rd fastest
② Work (PCI-Express Gen4 1TB) 2nd fastest
③ Cache (PCI-Express Gen4 1TB) 1st fastest
④ Data storage (3.5HDD 8TB)

I bought a new SSD to start UE5.
(PCI-Express Gen4 2TB) 2nd fastest

I would like you to tell me, is it better to save the engine, project, cache (DDC) separately for each SSD?

Below is what I’m thinking.

Install the engine in ①.
Create a project on the new SSD.
DDC cache is stored in ④.

or,

Create engine and project on new SSD.
DDC cache is stored on HDD.

Please let me know if there is a better way.