Yes you can.
Navigate to your fixture folder inside the content browser and create a new Blueprint actor class.
After creating the blueprint open it up, press the “Add component” button and select Static Mesh. Select the static mesh component you’ve just added and assign the fixture mesh to it. After that add another component and select a spot light (or whatever you want to use). Set up the light with the required default settings (such as the IES file that you wish to use) and move it to the required location.
Optionally you can drag and drop the light on on to the static mesh components to link its location / rotation.
You can duplicate the blueprint for however many fixtures you have and just replace the mesh and IES file for each one.