How to edit reference/bind pose bones at runtime?

Hello all,

I’m making a char creation setup and I want to apply certain transforms to the bones. As this will be kind of one time thing, a performance approach seems to be just to “bake” these transform in the reference/bind pose. So far, I know you can use Transform (modify) Bone in an Animation Blueprint, but this seems to be running all the time and 2nd, I have many, many bones to update, which further would add a penalty.

Advises how to handle that?