How Can We Use Morph Targets for Facial Expressions?

Hi. We’re working on a project right now, which includes facial expressions. I just searched on Google and YouTube about morph targets(blend shapes), and found couple of examples. The thing is, none of them converted these morph targets into a full in-game character. Is morph targets can be manipulated just like the bone animations? What happens if we activate the morph target while the actor moves his head realtime? We are in the rigging process right now and haven’t set anything about anim bp yet. We’re planning to move on when everything is ready and have been ensured. What’s more, some of these blendshapes are going to be used in cinematics.