Hey, don’t know if this helps, just had to deal with a similar problem, every software using UE4 was crashing.
CPU i9 9900k
GPU RTX 2080 Super
MoBo TUF Gaming z390 plus WiFi
Ram 3600mhz 32gb Corsair (can’t remember the clocks)
After reinstalling windows, downgrading, reinstalling, upgrading drivers I would always encounter the same issues, BSOD, app freezes, restarts, hangs.
Removed all USBs which didn’t help at all. I was also running some RTX demos to test it out, the reflections and the elemental one. The reflections didn’t work at all, got fatal errors after the loading and that was it.
I was ready to swap the GPU with a RTX 2070 super when I’ve decided to go to the BIOS, noticed that the ram was set to 3600mhz but the X.M.P profile was disabled, which means that most likely the wrong voltage was going into the RAMs.
For good measure restored the BIOS settings, enabled the X.M.P profile and restarted.
No more crashes after that, it’s been a good hour, reflections now runs and has been doing so for the past hour.
I blamed everything and everyone but it was actually my fault…
Last time I’ve upgraded the BIOS didn’t activate the X.M.P profile at all but changed the RAM frequency.
Not saying this is your problem but give it a shot.