Hello ,
Thank you for posting in the community your question and your interest in the 3d connexion devices support for the Mac version. At this time the functionality is only supported for Windows OS but we are planning on making it available for Mac as well. You can reference the limitation in the release notes here: https://twinmotionhelp.epicgames.com/s/article/Twinmotion-2022-1-Release-Notes
Also please note that at this time Monterey and M1 are not yet supported for Twinmotion and you may encounter limitations due to this. Below are two articles with more information on this.
https://twinmotionhelp.epicgames.com/s/article/TwinMotion-System-Requirements
https://twinmotionhelp.epicgames.com/s/article/Path-Tracer-Requirements
Thank you for your interest and patience while we work on this.
Kind regards,
Vincent B.