Alright, after doing more research online, I was able to find an odd fix. In blueprints, I had been deriving the location of the Target Points via the world location of their scene components. Replacing these nodes with “GetActorLocation” resolved the issue, and now the game spawns actors correctly.
This is still a very strange bug, though, and I look forward to seeing it resolved.
I found this solution here (Rudy Triplett’s answer):