For the record this plugin is still Experimental and is being developed. It may cause all sorts of problems because of this.
You can find more information on the forum about Paper2D.
I wasn’t sure where to post this so I am posting the question then answering it myself. I had a problem with one project that would not build or launch in the UE4 editor. After troubleshooting everything I realized that enabling the Paper 2D plugin caused this problem. Hope this helps anyone having this issue. I’m not sure if the problem persist with other plugins.
Peace