External file based location/rotation. Possible or not?

you can use arrays of vectors, lerps, and setActorLocation / SetActorRotation nodes to animate objects:

and you can load that vector data from a text file using functions found in CoreMisc.h:

FFileHelper::SaveStringToFile()
FFileHelper::LoadFileToString()

https://docs.unrealengine.com/latest/INT/API/Runtime/Core/Misc/FFileHelper/index.html

once you load the file into a string, you can parse it into an array of strings, splitting it at every comma, by using ParseIntoArray: