The previous version of the DLSS plugin for Unreal Engine 5 was working in VR but the new DLSS 4 plugin for UE 5.5 does not.
In my player controller at begin play I have the “Set DLSS/DLAA Mode (No Auto)” node set to performance mode and when I click play in VR my right eye is rendering solid black and the entire game window freezes.
The issue might not be related, as I don’t have VR stuff, but as an option, try disabling NIS. I’ve observed that it doesn’t work correctly with the latest DLSS version, and native smoothing or FSR 1 provide me with a better outcome.